Identification of decorin and chondroitin sulfate proteoglycans in turkey skeletal muscle.
نویسندگان
چکیده
Turkey pectoral muscles were examined at 15 through 25 d of embryonic age in order to delineate the developmental pattern of proteoglycan expression during skeletal muscle development. Glycosaminoglycan concentration, decorin, and muscle chondroitin sulfate proteoglycan (M-CSPG) levels were measured at each developmental age. Glycosaminoglycan levels rose during the developmental period studied, whereas decorin and M-CSPG levels were initially high at Day 15 and then decreased. The results from this study demonstrate the presence of both decorin and M-CSPG during turkey skeletal muscle development.
منابع مشابه
Developmental regulation of proteoglycan synthesis and decorin expression during turkey embryonic skeletal muscle formation.
To delineate the role of proteoglycans in turkey skeletal muscle development, proteoglycan expression was examined in pectoral muscle from 14-, 20-, and 25-d-old embryos. Proteoglycans were separated by DEAE (diethylaminoethyl cellulose) anion exchange and molecular sieve chromatography. Glycosaminoglycan composition was measured by enzyme digestion and nitrous acid deamination. The proteoglyca...
متن کاملIncrease in decorin and biglycan in Duchenne Muscular Dystrophy: role of fibroblasts as cell source of these proteoglycans in the disease
Fibrosis is a common pathological feature observed in muscles of patients with Duchenne muscular dystrophy (DMD). Biglycan and decorin are small chondroitin/dermatan sulfate proteoglycans in the muscle extracellular matrix (ECM) that belong to the family of structurally related proteoglycans called small leucine-rich repeat proteins. Decorin is considered an anti-fibrotic agent, preventing the ...
متن کاملDynamic Expression of Proteoglycans during Skeletal Muscle Development
Proteoglycans are glycoconjugates composed of a core protein and covalcntly attached glycosaminoglycans. Skeletal muscle produces a number of different types of proteogiycans, and, importantly, the types of proteogiycans made by skeletal muscle vary during muscle development. At early stages of muscle development, large chondroiim sulfate proteogiycans of the PG-M/versican type are produced bot...
متن کاملDetection of chondroitin sulfates and decorin in developing fetal and neonatal rat lung.
Chondroitin sulfates and their related proteoglycans are components of extracellular matrix that act as key determinants of growth and differentiation characteristics of developing lungs. Changes in their immunohistochemical distribution during progressive organ maturation were examined with monospecific antibodies to chondroitin sulfate, a nonbasement membrane chondroitin sulfate proteoglycan,...
متن کاملSequence analysis and domain motifs in the porcine skin decorin glycosaminoglycan chain.
Decorin proteoglycan is comprised of a core protein containing a single O-linked dermatan sulfate/chondroitin sulfate glycosaminoglycan (GAG) chain. Although the sequence of the decorin core protein is determined by the gene encoding its structure, the structure of its GAG chain is determined in the Golgi. The recent application of modern MS to bikunin, a far simpler chondroitin sulfate proteog...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Poultry science
دوره 76 3 شماره
صفحات -
تاریخ انتشار 1997